KRT20 Antibody / Cytokeratin 20 / CK20
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. KRT20 (Cytokeratin 20, CK20) is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P35900
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 196-323 from the human protein was used as the immunogen for this KRT20 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CTKN20-1
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the KRT20 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This KRT20 antibody is available for research use only.
Storage Conditions
Store the KRT20 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
Western blot testing of human HT29 cell lysate with KRT20 antibody (clone CTKN20-1) . Predicted molecular weight ~46 kDa.
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