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RPSA Antibody / 40S Ribosomal protein SA / Laminin Receptor 1

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1-2 µg/mL, Flow cytometry: 1-2ug/10^6 cells, Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)

UniProt

P08865

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full length protein was used as the immunogen for the RPSA antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

LMNR-1

Applications

IHC-P, WB, FACS, IF

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the RPSA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This RPSA antibody is available for research use only.

Storage Conditions

Store the RPSA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Location

Cell surface, cytoplasmic, nuclear

Image Legend

Western blot testing of human HeLa cell lysate with RPSA antibody (clone LMNR-1) . Routinely observed molecular weight: 37-40 kDa and 67 kDa.

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