Neuregulin-1 Antibody / NRG1
Heregulin-1 / Neuregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD) .
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA/sodium azide-free format for coating), Immunofluorescence: 1-2 µg/mL
UniProt
Q02297
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 21-242 from the human protein was used as the immunogen for this Neuregulin-1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
NRG1/2752
Applications
ELISA, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Neuregulin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Neuregulin-1 antibody is available for research use only.
Storage Conditions
Store the Neuregulin-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic, plasma membrane, nuclear
Image Legend
Immunofluorescent staining of human MCF7 cells with Neuregulin-1 antibody (clone NRG1/2752, green) and Reddot nuclear stain (red) .
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