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Recombinant TYRP1 Antibody / Tyrosinase Related Protein 1 / TRP1

Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P17643

Host

Rabbit

Reactivity

Human

Immunogen

Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

TYRP1/1564R

Type

Recombinant

Applications

IHC-P

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the recombinant TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant TYRP1 antibody is available for research use only.

Storage Conditions

Store the recombinant TYRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human melanoma with recombinant TYRP1 antibody, HRP secondary and AEC chromogen. HIER: steam sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min.

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