Recombinant WT1 Antibody / Rabbit Monoclonal
Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P19544
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A recombinant protein was used as the immunogen for the recombinant WT1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
WT1/1434R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant WT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant WT1 antibody is available for research use only.
Storage Conditions
Store the recombinant WT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Nuclear, cytoplasmic
Image Legend
Documents
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
PCNA (Proliferating Cell Nuclear Antigen) (Biotin)
