Recombinant IgG Antibody / Rabbit Monoclonal
Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P01857
Host
Rabbit
Reactivity
Human
Immunogen
Human Ig Gamma Chain was used as the immunogen for this recombinant IgG antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
IG507R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant IgG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant IgG antibody is available for research use only.
Storage Conditions
Store the recombinant IgG antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Cytoplasm, Cell Surface and Secreted
Image Legend
IHC testing of FFPE human tonsil with recombinant IgG antibody (clone IG507R) . HIER: steam sections in 10mM citrate buffer, pH 6.0, for 10-20 min.
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