Recombinant CD20 Antibody / Rabbit Monoclonal
CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It has been shown that CD20 plays a role in the microenvironmental interactions of B cells. [Wiki]
Product Specifications
CAS Number
9000-83-3
Specifications
UniProt
P11836
Host
Rabbit
Reactivity
Human
Immunogen
Full length human CD20 protein was used as the immunogen for this reccombinant CD20 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
RMC20-1
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Recombinant CD20 antibody with azide can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.
Limitations
This recombinant CD20 antibody is available for research use only.
Storage Conditions
Recombinant CD20 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Predominantly cell surface with some cytoplasmic
Image Legend
IHC testing of recombinant CD20 antibody and FFPE human tonsil tissue. HIER: steam section in pH 9 10mM Tris with 1mM EDTA for 20 min.
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