TL1A Antibody / VEGI / TNFSF15
TL1A is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF-alpha and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 (death receptor 3) and TNFRSF6B (decoy receptor 3) . It can activate both the NF-κB and MAPK signalling pathways, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
O95150
Host
Mouse
Reactivity
Human
Immunogen
A full length human recombinant protein was used as the immunogen for this TL1A antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
TLRM1-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the TL1A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TL1A antibody is available for research use only.
Storage Conditions
Store the TL1A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Cytoplasmic, cell surface, secreted
Image Legend
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