Recombinant TNF-alpha Antibody / Rabbit Monoclonal
The primary role of TNF is in the regulation of immune cells. TNFa, being an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, inflammation and to inhibit tumorigenesis and viral replication and respond to sepsis via IL1 & IL6 producing cells. Dysregulation of TNF production has been implicated in a variety of human diseases including Alzheimer's disease, cancer, major depression, Psoriasis and inflammatory bowel disease (IBD) . [Wiki]
Product Specifications
CAS Number
9000-83-3
Specifications
UniProt
P01375
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the recombinant TNF-alpha antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
RMTNFA-1
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the recombinant TNF-alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant TNF-alpha antibody is available for research use only.
Storage Conditions
Store the recombinant TNF-alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Applications Notes
Location
Cytoplasmic and extracellular (secreted)
Image Legend
Frequently Asked Questions
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