Adipophilin Antibody / Perilipin 2 / ADRP
Adipophilin, also called Perilipin 2, ADRP (Adipose differentiation related protein), and PLIN2, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material and maybe involved in development and maintenance of adipose tissue. It is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Western blot: 1-2 µg/mL
UniProt
Q99541
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant partial protein was used as the immunogen for this Adipophilin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ADPN1-1
Applications
WB, FACS
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
The Adipophilin antibody (with azide) can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.
Limitations
This Adipophilin antibody is available for research use only.
Storage Conditions
The Adipophilin antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Titering of the Adipophilin antibody may be required for optimal performance.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) partial recombinant protein and 2) Jurkat cell lysate using Adipophilin antibody (clone ADPN1-1) .
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