GRP94 Antibody / HSP90B1
Heat shock protein 90kDa beta member 1, known also as endoplasmin, gp96, grp94 and ERp99, is an HSP90 paralogue that is found in the endoplasmic reticulum. It plays critical roles in folding proteins in the secretory pathway such as Toll-like receptors and integrins. It has been implicated as an essential immune chaperone to regulate both innate and adaptive immunity. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistology (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P14625
Host
Rat
Reactivity
Human
Immunogen
Recombinant full-length human HSP90B1 protein was used as the immunogen for the GRP94 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
SRPR90b
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the GRP94 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This GRP94 antibody is available for research use only.
Storage Conditions
Store the GRP94 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic and nuclear
Image Legend
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