TRP1 Antibody / Tyrosinase-Related Protein-1 / TYRP1
Tyrosinase-Related Protein-1/TYRP1/TRP1 is a melanocyte-specific gene product involved in melanin synthesis. While mouse Tyrp1 possesses dihydroxyindole carboxylic acid oxidase activity, the function in human melanocytes is less clear. In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity. Tyrp1 is also involved in maintenance of melanosome structure and affects melanocyte proliferation and melanocyte cell death. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 3-6 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P17643
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
TYRR1-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TRP1 antibody is available for research use only.
Storage Conditions
Store the TRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Cytoplasmic
Image Legend
Frequently Asked Questions
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