VCAM-1 Antibody
Vascular cell adhesion molecule-1 (VCAM-1), also called L1CAM and CD106, is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P19320
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the VCAM-1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CDLA106
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the VCAM-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This VCAM-1 antibody is available for research use only.
Storage Conditions
Store the VCAM-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic, membrane
Image Legend
IHC testing of FFPE human tonsil with VCAM-1 antibody (clone CDLA106) .
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