SHBG Antibody

Sex Hormone Binding Globulin, also called Androgen Binding Protein (ABP) and Testosterone-Estradiol-Binding Globulin (TEBG), functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

P04278

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the SHBG antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

TTEB3

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the SHBG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This SHBG antibody is available for research use only.

Storage Conditions

Store the SHBG antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cytoplasmic & extracellular (secreted)

Image Legend

IHC testing of FFPE human testicular carcinoma with SHBG antibody (clone TTEB3) . Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.