SHBG Antibody

Sex Hormone Binding Globulin, also called Androgen Binding Protein (ABP) and Testosterone-Estradiol-Binding Globulin (TEBG), functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT (1), Prediluted IHC only format: incubate for 30 min at RT (2)

UniProt

P04278

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the SHBG antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

TTEB3

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the SHBG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This SHBG antibody is available for research use only.

Storage Conditions

Store the SHBG antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Location

Cytoplasmic & extracellular (secreted)

Image Legend

IHC testing of FFPE human testicular carcinoma with SHBG antibody (clone TTEB3) . Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.