Cytokeratin 18 Antibody
Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P05783
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human KRT18 protein was used as the immunogen for the Cytokeratin 18 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CTKN18-1
Applications
IF, IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Cytokeratin 18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Cytokeratin 18 antibody is available for research use only.
Storage Conditions
Store the Cytokeratin 18 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of permeabilized human MCF7 cells with Cytokeratin 18 antibody (clone CTKN18-1, green) and Reddot nuclear stain (red) .
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