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LHB Antibody / Luteinizing Hormone beta

Luteinizing Hormone beta/LHB is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH) . Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease. [RefSeq]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min RT (1)

UniProt

P01229

Host

Mouse

Reactivity

Human

Immunogen

Recombinant beta sub-unit of human LH was used as the immunogen for the LHB antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CCGD1

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the LHB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This LHB antibody is available for research use only.

Storage Conditions

Store the LHB antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the LHB antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min

Location

Cytoplasmic, secreted

Image Legend

IHC testing of FFPE human pituitary with LHB antibody (clone CCGD1) .

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