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MALT1 Antibody

Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)

Host

Mouse

Reactivity

Human

Immunogen

A recombinant fragment (aa 701-808) was used as the immunogen for this antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

4NMT-3

Applications

WB, IHC-P

Purity

Protein G purified

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Store the MALT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This MALT1 antibody is available for research use only.

Storage Conditions

Store the MALT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Titering of the MALT1 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Location

Cytoplasmic

Image Legend

Western blot testing of human Daudi lysate with MALT1 antibody (clone 4NMT-3) . Expected molecular weight ~92 kDa.

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