MALT1 Antibody
Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment (aa 701-808) was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
4NMT-3
Applications
WB, IHC-P
Purity
Protein G purified
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the MALT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This MALT1 antibody is available for research use only.
Storage Conditions
Store the MALT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Western blot testing of human Daudi lysate with MALT1 antibody (clone 4NMT-3) . Expected molecular weight ~92 kDa.
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