SUMO2/3 Antibody
The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. SUMO proteins are synthesized as precursors that undergo processing before conjugation to target proteins. Sumoylation targets for a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. SUMO2/3 contribute to a greater percentage of protein modification than does SUMO1 and they can form polymeric chains. In addition, SUMO3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer�s disease.
Product Specifications
CAS Number
9007-83-4
Specifications
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human SUMO2 protein was used as the immunogen for this SUMO2/3 antibody. This antibody reacts with both SUMO2 and SUMO3.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
S23MT-1
Applications
WB, IHC-P, IF
Purity
Protein G purified
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the SUMO2/3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This SUMO2/3 antibody is available for research use only.
Storage Conditions
Store the SUMO2/3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Predominantly nuclear with some cytoplasmic staining
Image Legend
Western blot testing of human HeLa lysate with SUMO2/3 antibody (clone S23MT-1) .
Frequently Asked Questions
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