PAX6 Antibody
PAX6 is a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [RefSeq]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL
Host
Mouse
Reactivity
Human
Immunogen
A partial human PAX6 protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PBPX6
Applications
WB
Purity
Protein G purified antibody
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the PAX6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PAX6 antibody is available for research use only.
Storage Conditions
Store the PAX6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Nuclear
Image Legend
Western blot analysis of human cerebellum and PAX6 antibody (clone PBPX6) . Predicted molecular weight ~48 kDa.
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