CEA Antibody / CEACAM5
CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+) .
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT (1), Prediluted IHC only format: incubate for 30 min at RT (2)
UniProt
P06731
Host
Mouse
Reactivity
Human
Immunogen
Human full-length recombinant protein was used as the immunogen for this CEA antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
CCM661
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CEA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CEA antibody is available for research use only.
Storage Conditions
Store the CEA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic and luminal surface
Image Legend
FFPE staining of human colon carcinoma with CEA antibody (CCM661) .
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