Recombinant Secretory Component Glycoprotein Antibody / ECM1

Extracellular matrix protein 1 (ECM1), also called Secretory component p85, a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

Q16610

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the Secretory Component Glycoprotein antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG1 k

Clone

SRGP85

Type

Recombinant

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the Secretory Component Glycoprotein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Secretory Component Glycoprotein antibody is available for research use only.

Storage Conditions

Store the Secretory Component Glycoprotein antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cell surface and cytoplasmic

Image Legend

IHC testing of FFPE human colon carcinoma and Secretory Component Glycoprotein antibody (clone SRGP85) . Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.