FXN Antibody / Frataxin
Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q16595
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
FXN/2124
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the FXN antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FXN antibody is available for research use only.
Storage Conditions
Store the FXN antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
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