AKR1B1 Antibody / Aldose reductase
AKR1B1, also deisgnated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P15121
Host
Mouse
Reactivity
Human
Immunogen
Recombinant protein was used as the immunogen for this AKR1B1 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
CPTC-AKR1B1-2
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the AKR1B1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This AKR1B1 antibody is available for research use only.
Storage Conditions
Store the AKR1B1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic, nuclear
Image Legend
Documents
Frequently Asked Questions
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