AURKB Antibody / Aurora B
Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q96GD4
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 89-251 were used as the immunogen for this AURKB antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
ARRK2-1
Applications
IHC-P
Purity
Protein G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This AURKB antibody is available for research use only.
Storage Conditions
Store the AURKB antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the AURKB antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
P27 / KIP1 (DCS-72.F6 + KIP1/769 (SX53G8) ), 0.2mg/mL
