NGF Receptor Antibody
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P08138
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human partial protein corresponding to amino acids 281-421 was used as the immunogen for the NGF Receptor antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
NGFR/1964
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the NGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This NGF Receptor antibody is available for research use only.
Storage Conditions
Store the NGF Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the NGF Receptor antibody should be determined by the researcher.
Location
Cell surface and cytoplasmic
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![FITC Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80e85/imageurl/ha600116f.webp)
FITC Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
![5 (6) -FAM, SE [5- (and-6) -Carboxyfluorescein, succinimidyl ester] *CAS 117548-22-8*](https://cdn.genprice.uk/products/271/7358460/imageurl/110-aat.webp)
5 (6) -FAM, SE [5- (and-6) -Carboxyfluorescein, succinimidyl ester] *CAS 117548-22-8*
