TLE1 Antibody / Transducin-like enhancer protein 1
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q04724
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 175-338 from the human protein was used as the immunogen for the TLE1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
TLEP1-1
Applications
IHC-P, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the TLE1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TLE1 antibody is available for research use only.
Storage Conditions
Store the TLE1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Nuclear
Image Legend
Western blot testing of human HeLa cell lysate with TLE1 antibody (clone TLEP1-1) . Predicted molecular weight ~83 kDa.
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