PU.1 Antibody / SPI1
Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Immunofluorescence: 1-2 µg/mL, Western blot: 1-2 µg/mL
UniProt
P17947
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 16-170 from the human protein was used as the immunogen for the PU.1 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
TFPU1-1
Applications
IHC-P, WB, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the PU.1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PU.1 antibody is available for research use only.
Storage Conditions
Store the PU.1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Location
Nuclear
Image Legend
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