TROP2 Antibody / TACSTD2
TACSTD2, also called TROP2, is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P09758
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 31-274 were used as the immunogen for the TROP2 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
TACSTD2/2151
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the TROP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TROP2 antibody is available for research use only.
Storage Conditions
Store the TROP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the TROP2 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
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