GP2 Antibody / Glycoprotein 2 / ZAP75

The GP2 gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD) . [RefSeq]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P55259

Host

Mouse

Reactivity

Human

Immunogen

A human recombinant partial protein (aa 35-179) was used as the immunogen for the GP2 antibody.

Clonality

Monoclonal

Isotype

IgG2c κ

Clone

PSGMG2-1

Applications

IHC-P, WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the GP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This GP2 antibody is available for research use only.

Storage Conditions

Store the GP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the GP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, membranous, secreted

Image Legend

IHC testing of FFPE human pancreas with GP2 antibody (clone PSGMG2-1) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.