Cefquinome

Cefquinome is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae[1][2][3].

Product Specifications

CAS Number

[84957-30-2]

UNSPSC

12352005

Hazard Statement

H317-H334

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefquinome.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC)=O)[C@@]3([H])SCC(C[N+]4=C5CCCCC5=CC=C4)=C(C([O-])=O)N13

Molecular Formula

C23H24N6O5S2

Molecular Weight

528.60

Precautions

P261-P272-P280-P284-P302+P352-P304+P340-P362+P364-P501

References & Citations

[1]Chin NX, et al. In vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics. Diagn Microbiol Infect Dis. 1992 May-Jun;15 (4) :331-7.|[2]Qu S, et al., Cefquinome-loaded microsphere formulations against Klebsiella pneumonia infection during experimental infections. Drug Deliv. 2018 Nov;25 (1) :909-915.|[3]Limbert M, et al., Antibacterial activities in vitro and in vivo and pharmacokinetics of cefquinome (HR 111V), a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1991 Jan;35 (1) :14-9.