What is the catalog number for CD14 Antibody (Macrophage Marker)?

The catalog number for CD14 Antibody (Macrophage Marker) is V3764SAF-100UG.

What sizes are available for CD14 Antibody (Macrophage Marker)?

CD14 Antibody (Macrophage Marker) is available in the following size(s): 100 µg.

Is CD14 Antibody (Macrophage Marker) in stock?

CD14 Antibody (Macrophage Marker) is currently made to order / not held in immediate stock. Contact us for lead time.

CD14 Antibody (Macrophage Marker)

Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) . Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

IHC (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 1-2 µg/mL

UniProt

P08571

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 25-148 was used as immunogen for this CD14 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CDLA14-2

Applications

IHC-P, WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the CD14 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD14 antibody is available for research use only.

Storage Conditions

Store the CD14 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CD14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cell surface, Secreted, Cytoplasmic (Golgi)

Image Legend

IHC testing of FFPE human lymph node with CD14 antibody (clone CDLA14-2) . HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.