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Recombinant Cadherin 16 Antibody / Rabbit Monoclonal

The CDH16 gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. Cadherin 16 consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. [Wiki]

Product Specifications

CAS Number

9000-83-3

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

O75309

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Human protein was used as the immunogen for the recombinant Cadherin 16 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

KSCP2-2R

Type

Recombinant

Applications

IHC-P

Purity

Protein A affinity chromatography

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the recombinant Cadherin 16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant Cadherin 16 antibody is available for research use only.

Storage Conditions

Store the recombinant Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cell surface with some cytoplasmic

Image Legend

IHC testing of FFPE human renal cell carcinoma with recombinant Cadherin 16 antibody (clone KSCP2-2R) . Required HIER: steam sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min.

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