Recombinant CD61 Antibody / Integrin beta 3 / ITGB3
CD61 associates with CD51 to form vitronectin receptor, or with CD41 to form the CD41/CD61 complex. The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 complex is implicated in tumor metastasis and adenoviral infection.
Product Specifications
CAS Number
9000-83-3
Specifications
IHC (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format : incubate for 30 min at RT (1)
UniProt
P05106
Host
Rabbit
Reactivity
Human
Immunogen
Human recombinant protein was used as the immunogen for the recombinant CD61 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
PMGP3-1R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant CD61 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant CD61 antibody is available for research use only.
Storage Conditions
Store the recombinant CD61 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cell surface, cytoplasmic
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