Recombinant Chromogranin A Antibody

Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins, i.e., it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in pancreas. Chromogranin A is the precursor to several functional peptides including vasostatin-1, vasostatin-2, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine) . [Wiki]

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)

UniProt

P10645

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant human protein was used as the immunogen for the recombinant Chromogranin A antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

BGRAN2R

Type

Recombinant

Applications

IHC-P

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the recombinant Chromogranin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant Chromogranin A antibody is available for research use only.

Storage Conditions

Store the recombinant Chromogranin A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Location

Cytoplasmic

Image Legend

IHC analysis of FFPE human parathyroid gland stained with recombinant Chromogranin A antibody (clone bGRAN2R) . Required HIER: steam sections in pH6 citrate buffer for 10-20 min and allow to cool at RT for 20 min before testing.