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PI-55

PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins induced haustorium formation and increased parasite aggressiveness[1].

Product Specifications

CAS Number

[1122579-42-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pi-55.html

Concentration

10mM

Purity

98.89

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=C(CNC2=C3N=CNC3=NC=N2)C=CC=C1C

Molecular Formula

C13H13N5O

Molecular Weight

255.28

Precautions

H302, H315, H319, H335

References & Citations

[1] Goyet V, et al. Haustorium initiation in the obligate parasitic plant Phelipanche ramosa involves a host-exudated cytokinin signal. J Exp Bot. 2017;68 (20) :5539-5552.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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