Recombinant GYPA Antibody / Glycophorin A

Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175) ; binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV) . [UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 0.25-0.5 µg/mL for 30 min at RT

UniProt

P02724

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human Glycophorin A protein was used as the immunogen for the recombinant GYPA antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG1 k

Clone

RGYPA/280

Type

Recombinant

Applications

IHC-P, WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the recombinant GYPA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant GYPA antibody is available for research use only.

Storage Conditions

Store the recombinant GYPA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Location

Cytoplasmic, membranous

Image Legend

IHC testing of FFPE human angiosarcoma with recombinant GYPA antibody (clone rGYPA/280) . Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.