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Recombinant PAX5 Antibody

The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Product Specifications

CAS Number

9000-83-3

Specifications

ELISA (purchase BSA-free format for coating), Western blot: 1-2 µg/mL

UniProt

Q02548

Host

Mouse

Reactivity

Human

Immunogen

Human recombinant protein was used as the immunogen for this recombinant PAX5 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG1 k

Clone

RPAX5/2060

Type

Recombinant

Applications

ELISA, WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the recombinant PAX5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This recombinant PAX5 antibody is available for research use only.

Storage Conditions

Store the recombinant PAX5 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Location

Nuclear

Image Legend

Western blot testing of human Raji cell lysate with recombinant PAX5 antibody (clone rPAX5/2060) . Expected molecular weight ~42 kDa.

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