Recombinant PAX5 Antibody
The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA (purchase BSA-free format for coating), Western blot: 1-2 µg/mL
UniProt
Q02548
Host
Mouse
Reactivity
Human
Immunogen
Human recombinant protein was used as the immunogen for this recombinant PAX5 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RPAX5/2060
Type
Recombinant
Applications
ELISA, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant PAX5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant PAX5 antibody is available for research use only.
Storage Conditions
Store the recombinant PAX5 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear
Image Legend
Western blot testing of human Raji cell lysate with recombinant PAX5 antibody (clone rPAX5/2060) . Expected molecular weight ~42 kDa.
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