Recombinant RB1 Antibody / Rabbit Monoclonal
Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P06400
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A human recombinant partial protein was used as immunogen for this recombinant RB1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
RB1/2313R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
The recombinant RB1 antibody (with azide) can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.
Limitations
This recombinant RB1 antibody is available for research use only.
Storage Conditions
The recombinant RB1 antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![PE/Cyanine7 Anti-Rat CD90/Mouse CD90.1 Antibody[OX-7]](https://cdn.genprice.uk/products/763/68dd14a6061270361e7d1c6b/imageurl/e-ab-f1226h.webp)
PE/Cyanine7 Anti-Rat CD90/Mouse CD90.1 Antibody[OX-7]
PE/Cyanine7 Anti-Rat CD90/Mouse CD90.1 Antibody[OX-7]
PE/Cyanine7 Anti-Rat CD90/Mouse CD90.1 Antibody[OX-7]
