Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

3- (4-Hydroxy-1-oxoisoindolin-2-yl) piperidine-2,6-dione

Selected Variant

HY-W076696-01

Size: 250 mg

Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-OH can be connected to the ligand for protein by a linker to form PROTAC.

Product Specifications

CAS Number

1061604-41-8

UNSPSC

12352005

Hazard Statement

H302, H312, H315, H319

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lenalidomide-4-oh.html

Purity

99.62

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C(N(CC1=C2C=CC=C1O)C2=O)CC3)NC3=O

Molecular Formula

C13H12N2O4

Molecular Weight

260.25

Precautions

H302, H312, H315, H319

References & Citations

[1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Available Sizes

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-PGK1 Antibody Picoband® (Dylight488 Conjugate)
PB9774-Dylight488 100 µg

Anti-PGK1 Antibody Picoband® (Dylight488 Conjugate)

Sign In for Pricing
View Details
16S V1-V2 Library Preparation Kit for Illumina
70100 24 Preparations

16S V1-V2 Library Preparation Kit for Illumina

Sign In for Pricing
View Details
Anti-Grp75/HSPA9 Antibody Picoband®, PE Conjugate
PA1789-PE 100 µg/Vial

Anti-Grp75/HSPA9 Antibody Picoband®, PE Conjugate

Sign In for Pricing
View Details
Anti-NCKAP1 Antibody Picoband®
A09238-1 100 µg/Vial

Anti-NCKAP1 Antibody Picoband®

Sign In for Pricing
View Details