Growth Hormone Antibody (pituitary)

GH is a stress hormone that raises the concentration of glucose and free fatty acids. It also stimulates production of IGF-1. The major isoform of the human growth hormone is a protein of 191 amino acids and a molecular weight of 22,124 daltons. The structure includes four helices necessary for functional interaction with the GH receptor. It appears that, in structure, GH is evolutionarily homologous to prolactin and chorionic somatomammotropin. [Wiki]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P01241

Host

Mouse

Reactivity

Human

Immunogen

Amino acids 58-187 from the human protein were used as the immunogen for this Growth Hormone antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

GH/1371

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Store the Growth Hormone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Growth Hormone antibody is available for research use only.

Storage Conditions

Store the Growth Hormone antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Titration of the Growth Hormone antibody may be needed for optimal performance.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human pituitary gland with Growth Hormone antibody (clone GH/1371) . Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.