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MCM7 Antibody

MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

Product Specifications

UniProt

P33993

Host

Mouse

Immunogen

A human full length recombinant protein was used as the immunogen for the MCM7 antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

WB, IHC-P

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the MCM7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This MCM7 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6697269/datasheet/v3377-20ug.pdf

CAS Number

9007-83-4

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