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TIMP2 Antibody

It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Product Specifications

UniProt

P16035

Host

Mouse

Immunogen

An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Applications

IHC-P

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This TIMP2 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6697265/datasheet/v3376-100ug.pdf

CAS Number

9007-83-4

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