Ent-Toddalolactone
Ent-Toddalolactone is a natural compound with anti-inflammatory and anticancer activities. Ent-Toddalolactone has shown inhibitory effects on phosphodiesterase-4 (PDE4) in vitro and is a potential drug target for inhibiting asthma and chronic obstructive pulmonary disease. The activity of ent-Toddalolactone is related to its unique chemical structure, and some of its derivatives showed IC50 values below 10 μM in inhibition experiments, showing high biological activity[1].
Product Specifications
CAS Number
[1570054-19-1]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ent-toddalolactone.html
Smiles
CC(C)(O)[C@@H](O)CC1=C(OC)C=C(OC(C=C2)=O)C2=C1OC
Molecular Formula
C16H20O6
Molecular Weight
308.33
References & Citations
[1]Prenylated coumarins: natural phosphodiesterase-4 inhibitors from Toddalia asiatica
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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ENTPD3, CT (ENTPD3, CD39L3, Ectonucleoside triphosphate diphosphohydrolase 3, CD39 antigen-like 3, Ecto-ATP diphosphohydrolase 3, Ecto-apyrase 3, HB6) (MaxLight 490)
