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Ent-Toddalolactone

Ent-Toddalolactone is a natural compound with anti-inflammatory and anticancer activities. Ent-Toddalolactone has shown inhibitory effects on phosphodiesterase-4 (PDE4) in vitro and is a potential drug target for inhibiting asthma and chronic obstructive pulmonary disease. The activity of ent-Toddalolactone is related to its unique chemical structure, and some of its derivatives showed IC50 values below 10 μM in inhibition experiments, showing high biological activity[1].

Product Specifications

CAS Number

[1570054-19-1]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ent-toddalolactone.html

Smiles

CC(C)(O)[C@@H](O)CC1=C(OC)C=C(OC(C=C2)=O)C2=C1OC

Molecular Formula

C16H20O6

Molecular Weight

308.33

References & Citations

[1]Prenylated coumarins: natural phosphodiesterase-4 inhibitors from Toddalia asiatica

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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