What is the catalog number for CD105 Antibody / Endoglin?

The catalog number for CD105 Antibody / Endoglin is V3340-100UG.

What sizes are available for CD105 Antibody / Endoglin?

CD105 Antibody / Endoglin is available in the following size(s): 100 µg.

Is CD105 Antibody / Endoglin in stock?

CD105 Antibody / Endoglin is currently made to order / not held in immediate stock. Contact us for lead time.

CD105 Antibody / Endoglin

CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. CD105 has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. It is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL

UniProt

P17813

Host

Mouse

Reactivity

Human

Immunogen

A partial recombinant protein corresponding to amino acids 74-251 of human CD105/Endoglin was used as the immunogen for the CD105 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

ENG/1326

Applications

WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the CD105 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD105 antibody is available for research use only.

Storage Conditions

Store the CD105 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Titering of the CD105 antibody may be required for optimal performance.

Location

Cell surface, cytoplasmic

Image Legend

Western blot testing of human 1) HeLa, 2) A431 and 3) HL60 cell lysate with CD105 antibody (clone ENG/1326) . Observed molecular weight: 70/90 kDa (monomer, unmodified/glycosylated) ; 140-180 kDa (dimer, unmodified/glycosylated) .