LGALS13 Antibody / Galectin 13
It recognizes a 32kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13) . Galectins are a family of soluble β -galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, LGALS13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, LGALS13 exists as a disulfide-linked homodimer. LGALS13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for LGALS13/Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA/sodium azide-free format for coating), Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
Q9UHV8
Host
Mouse
Reactivity
Human
Immunogen
A human partial recombinant protein corresponding to amino acids 23-134 was used as the immunogen for the LGALS13 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
PP13/1165
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the LGALS13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This LGALS13 antibody is available for research use only.
Storage Conditions
Store the LGALS13 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Titering of the LGALS13 antibody may be required for optimal performance.
Location
Cytoplasmic, cell surface
Image Legend
Documents
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
