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Desmoglein 3 Antibody / DSG3

Desmoglein 3 is a component of intercellular desmosome junctions. It is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P32926

Host

Mouse

Reactivity

Human

Immunogen

A protein fragment corresponding to the extracellular portion of human DSG3 was used as the immunogen for the Desmoglein 3 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

DSG3/1535

Applications

WB, IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the Desmoglein 3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Desmoglein 3 antibody is available for research use only.

Storage Conditions

Store the Desmoglein 3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Desmoglein 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cell surface

Image Legend

IHC testing of FFPE human skin with Desmoglein 3 antibody (clone DSG3/1535) . Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.

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