CFTR Antibody
Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P13569
Host
Mouse
Reactivity
Human
Immunogen
Human partial recombinant protein was used as the immunogen for this CFTR antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
SPM176
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CFTR antibody is available for research use only.
Storage Conditions
Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Location
Cell surface, cytoplasmic
Image Legend
IHC testing of FFPE human pancreas with CFTR antibody (clone SPM176) . HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.
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